Equivalence classes and their many uses in RNA-seq analyses
If you’re performing an RNA-seq experiment, there’s a good chance that aligning to the genome will be one of the key steps in your workflow. The mapping loca...
Recent Posts
Behind the Paper: Inferring structural variant cancer cell fraction
Over the past two decades, the field of biology has been transitioning from small data to big data, and my PhD journey followed a similar trend. While workin...
My PhD explained using the 1,000 most common English words
After listening to an Intelligence Squared podcast episode on making complicated stuff simple, I was inspired to explain my recently submitted PhD thesis usi...
The problem with perfect phylogenies
Previously, I wrote a blog post, exploring the Gusfield algorithm for building phylogenetic trees from binary traits. While the algorithm works well if you h...
Frequently asked questions about bioinformatics
These are my attempts at answering some of the questions I see come up on the r/bioinformatics sub-reddit or questions I get asked in real life about the fie...
Building phylogenetic trees with binary traits
For decades of its (at least) 200 year-long history, phylogenetics has been using DNA sequences to gain insight into the evolutionary history of species. Per...